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F150 · 09-15-2020, 05:48 AM

This has been a goal yet never accomplishes....yet. Would be a huge breakthrough for health care for sure.

WASHINGTON
Scientists at the Walter Reed Army Institute of Research are advancing a vaccine that may be able to prevent strains of the common cold in the future.

But their immediate concern is the imminent flu season because nearly seven months since receiving their first samples of the novel coronavirus from a Washington state patient, they still don’t know whether catching the flu could increase the chances of getting COVID-19.

“When this virus emerged, it was sort of coming toward the tail end of the flu season. And now we have both, at the same time, and we don’t know what that’s going to look like,” said Dr. Kayvon Modjarrad, director of emerging infectious diseases at Walter Reed in Maryland. “If you get sick with flu, is that going to make you more susceptible of getting COVID or risk of it, or vice versa? We don’t know that.”

VACCINE FOR SOME COMMON COLDS
The vaccine that Modjarrad and his team are working on would target not just COVID-19, but also other coronavirus-related illnesses, including several variants of the common cold.

“Most children, by age two or three, have been infected with one of these common cold coronaviruses,” Modjarrad said. “I don’t think people are really focused on trying to prevent the common cold, but that is, I think, an important side benefit of what we are trying to do,” he told McClatchy in an interview.

While the Walter Reed vaccine candidate is currently focused on COVID-19, the lab has structured the vaccine to be able to target different types of coronavirus. Once they have “proof of concept” that the vaccine is safe and effective, Modjarrad said, the Army lab will decide whether to pivot their efforts to creating the “pan-coronavirus” vaccine that would help prevent the common cold and other potential novel coronaviruses.

Modjarrad said that they are currently testing their vaccine in monkeys, and depending on the results, will enter into human trials toward the end of the year.

From preliminary research in mice, the vaccine has generated “extremely high levels of antibodies” that neutralize the coronavirus, and has also demonstrated a strong safety profile, he said.

Walter Reed’s researchers have also found that there is very little mutation occuring in the virus. That means just one vaccine could work for the entire global population — whether the COVID-19 variant originated in China or whether it was the one that came into the United States from Europe, which is the most common type now, said Dr. Morgane Rolland, chief of viral genetics for the Henry M. Jackson Foundation, which is supporting Walter Reed’s research.

“There’s really one strain, and that’s enough to make a vaccine,” Rolland said. “In terms of vaccine purposes, the virus is not a moving target.”

Rolland’s team just finished looking at the genetic sequences of 27,000 people who have had COVID. Viruses will mutate when spreading from one human to another, or an animal to human, because of the chance that not all of the tens of thousands of genomes will replicate exactly when they enter a new host, Rolland said.

What Rolland’s team found is that there were very few mutations. They think that is because COVID-19 spread so rapidly that the virus didn’t have a chance to mutate.

“At this point the vaccine would cover all the diversities that we are seeing in sequences that are spreading around the world,” Rolland said.

FLU SHOTS ‘BRING DOWN THE BURDEN’
Modjarrad said that individuals should not be concerned with receiving a flu vaccine in close proximity to an eventual vaccine for COVID-19, and encouraged all Americans to get vaccinated for the flu early in the season.

“I think it’s important that we have people understand that we have some of these effective tools in place that could actually indirectly bring down the burden of disease and death for COVID-19 by doing our due diligence in taking care of the flu as well,” Modjarrad said.

A flu shot does not make the individual more susceptible to getting ill, and it will not interfere with a potential COVID vaccine, as neither contain live virus, Modjarrad said.

A flu mist or nose spray that is taken instead of a shot, does use live flu virus. He recommends that any live-virus vaccines be spaced out and not administered at the same time as another live-virus vaccine, such as for measles.

At the outset of flu season, public health experts have grown increasingly concerned that the annual pressures on hospitals and health care workers will be exacerbated by the pandemic coronavirus, which spreads more easily without heat and humidity and has already led to nearly 200,000 deaths in the United States.

The flu kills tens of thousands of Americans each year, and hospitalizes hundreds of thousands, raising concerns about straining the availability of hospital beds and personal protective equipment for frontline workers that may be needed in the event of a coronavirus surge.

dlphg9 · 09-15-2020, 07:24 AM

In before

"Im never getting the flu shot again! Ive never been sick and one year I decided to get the flu shot and have never been more sick in my life!"

Hog's Gone Fishin · 09-15-2020, 07:30 AM

There's already a cure for the common cold

Dumbass!

**loochy** · 09-15-2020, 08:50 AM

Quote:

Originally Posted by dlphg9

In before

"Im never getting the flu shot again! Ive never been sick and one year I decided to get the flu shot and have never been more sick in my life!"

I aint never got no flu but wun time I got that dang ol flu shot and it made me get the flu gash durnit dag nabbit

eDave · 09-15-2020, 08:52 AM

Sometimes I like getting a cold so I can take a couple of sick days without feeling bad emotionally.

htismaqe · 09-15-2020, 08:59 AM

The headline really doesn't do the article justice.

It's not a cure for the common cold. It's a vaccine for COVID that may also have an effect on some strains of the common cold.

**loochy** · 09-15-2020, 09:04 AM

I'm more interested in a cure for the common old

eDave · 09-15-2020, 09:06 AM

Quote:

Originally Posted by loochy

I'm more interested in a cure for the common old

Give me my 40's, forever.

L.A. Chieffan · 09-15-2020, 09:15 AM

Antifreeze

**loochy** · 09-15-2020, 09:17 AM

Quote:

Originally Posted by eDave

Give me my 40's, forever.

I'm about to enter mine. Things are pretty good, but I get tired easier, my hair is thinning substantially, and I'm getting some major laugh line wrinkles.

eDave · 09-15-2020, 09:22 AM

Quote:

Originally Posted by loochy

I'm about to enter mine. Things are pretty good, but I get tired easier, my hair is thinning substantially, and I'm getting some major laugh line wrinkles.

Damn. Sorry man.

**loochy** · 09-15-2020, 09:25 AM

Quote:

Originally Posted by eDave

Damn. Sorry man.

Meh, it's not all that bad. The hair was accelerated by testosterone, so the trade off is fine with me. I'll just buzz it short when it gets to the point of looking stupid. The laugh lines will disappear with a bit of HLA.

The tiredness? I'll just win the lottery and then I can take a damn nap every day.

Eleazar · 09-15-2020, 09:29 AM

Quote:

Originally Posted by loochy

I'm about to enter mine. Things are pretty good, but I get tired easier, my hair is thinning substantially, and I'm getting some major laugh line wrinkles.

prayers sent

htismaqe · 09-15-2020, 09:47 AM

Quote:

Originally Posted by loochy

Meh, it's not all that bad. The hair was accelerated by testosterone, so the trade off is fine with me. I'll just buzz it short when it gets to the point of looking stupid. The laugh lines will disappear with a bit of HLA.

The tiredness? I'll just win the lottery and then I can take a damn nap every day.

I do take a nap every day. Working from home has its benefits.

In fact, I think I will go take one right now.

scho63 · 09-15-2020, 01:17 PM

When I get a cold it last 24-48 hours max and it's gone. Usually just a running nose, slight chills an feeling a little weak for the day.

I RARELY get a cold or flu. Sinus infections, that's a whole other story.

09-15-2020, 05:48 AM
F150 Veteran F150's Avatar Join Date: Jan 2020 Location: Missouri	Cure for the common cold? This has been a goal yet never accomplishes....yet. Would be a huge breakthrough for health care for sure. WASHINGTON Scientists at the Walter Reed Army Institute of Research are advancing a vaccine that may be able to prevent strains of the common cold in the future. But their immediate concern is the imminent flu season because nearly seven months since receiving their first samples of the novel coronavirus from a Washington state patient, they still don’t know whether catching the flu could increase the chances of getting COVID-19. “When this virus emerged, it was sort of coming toward the tail end of the flu season. And now we have both, at the same time, and we don’t know what that’s going to look like,” said Dr. Kayvon Modjarrad, director of emerging infectious diseases at Walter Reed in Maryland. “If you get sick with flu, is that going to make you more susceptible of getting COVID or risk of it, or vice versa? We don’t know that.” VACCINE FOR SOME COMMON COLDS The vaccine that Modjarrad and his team are working on would target not just COVID-19, but also other coronavirus-related illnesses, including several variants of the common cold. “Most children, by age two or three, have been infected with one of these common cold coronaviruses,” Modjarrad said. “I don’t think people are really focused on trying to prevent the common cold, but that is, I think, an important side benefit of what we are trying to do,” he told McClatchy in an interview. While the Walter Reed vaccine candidate is currently focused on COVID-19, the lab has structured the vaccine to be able to target different types of coronavirus. Once they have “proof of concept” that the vaccine is safe and effective, Modjarrad said, the Army lab will decide whether to pivot their efforts to creating the “pan-coronavirus” vaccine that would help prevent the common cold and other potential novel coronaviruses. Modjarrad said that they are currently testing their vaccine in monkeys, and depending on the results, will enter into human trials toward the end of the year. From preliminary research in mice, the vaccine has generated “extremely high levels of antibodies” that neutralize the coronavirus, and has also demonstrated a strong safety profile, he said. Walter Reed’s researchers have also found that there is very little mutation occuring in the virus. That means just one vaccine could work for the entire global population — whether the COVID-19 variant originated in China or whether it was the one that came into the United States from Europe, which is the most common type now, said Dr. Morgane Rolland, chief of viral genetics for the Henry M. Jackson Foundation, which is supporting Walter Reed’s research. “There’s really one strain, and that’s enough to make a vaccine,” Rolland said. “In terms of vaccine purposes, the virus is not a moving target.” Rolland’s team just finished looking at the genetic sequences of 27,000 people who have had COVID. Viruses will mutate when spreading from one human to another, or an animal to human, because of the chance that not all of the tens of thousands of genomes will replicate exactly when they enter a new host, Rolland said. What Rolland’s team found is that there were very few mutations. They think that is because COVID-19 spread so rapidly that the virus didn’t have a chance to mutate. “At this point the vaccine would cover all the diversities that we are seeing in sequences that are spreading around the world,” Rolland said. FLU SHOTS ‘BRING DOWN THE BURDEN’ Modjarrad said that individuals should not be concerned with receiving a flu vaccine in close proximity to an eventual vaccine for COVID-19, and encouraged all Americans to get vaccinated for the flu early in the season. “I think it’s important that we have people understand that we have some of these effective tools in place that could actually indirectly bring down the burden of disease and death for COVID-19 by doing our due diligence in taking care of the flu as well,” Modjarrad said. A flu shot does not make the individual more susceptible to getting ill, and it will not interfere with a potential COVID vaccine, as neither contain live virus, Modjarrad said. A flu mist or nose spray that is taken instead of a shot, does use live flu virus. He recommends that any live-virus vaccines be spaced out and not administered at the same time as another live-virus vaccine, such as for measles. At the outset of flu season, public health experts have grown increasingly concerned that the annual pressures on hospitals and health care workers will be exacerbated by the pandemic coronavirus, which spreads more easily without heat and humidity and has already led to nearly 200,000 deaths in the United States. The flu kills tens of thousands of Americans each year, and hospitalizes hundreds of thousands, raising concerns about straining the availability of hospital beds and personal protective equipment for frontline workers that may be needed in the event of a coronavirus surge.
Posts: 3,149

09-15-2020, 07:24 AM	#2
dlphg9 MVP dlphg9's Avatar Join Date: Oct 2010	In before "Im never getting the flu shot again! Ive never been sick and one year I decided to get the flu shot and have never been more sick in my life!"
Posts: 16,837	3 0

09-15-2020, 07:30 AM	#3
Hog's Gone Fishin Fish are scared of me Hog's Gone Fishin's Avatar Join Date: Nov 2001	There's already a cure for the common cold Dumbass!
Posts: 40,342

09-15-2020, 08:52 AM	#5
eDave Banned Join Date: Jan 2013	Sometimes I like getting a cold so I can take a couple of sick days without feeling bad emotionally.
Posts: 53,803	2 0

09-15-2020, 08:59 AM	#6
htismaqe 'Tis my eye! htismaqe's Avatar Join Date: Aug 2000 Location: Chiefsplanet	The headline really doesn't do the article justice. It's not a cure for the common cold. It's a vaccine for COVID that may also have an effect on some strains of the common cold.
Posts: 100,022

09-15-2020, 09:04 AM	#7
loochy Hey Loochy, I'm hooome! loochy's Avatar Join Date: Oct 2008 Location: PooPooKaKaPeePeeShire	I'm more interested in a cure for the common old
Posts: 40,458

09-15-2020, 09:15 AM	#9
L.A. Chieffan PLAY GOOD FOOTBALL L.A. Chieffan's Avatar Join Date: Aug 2006 Location: American Gardens Building	Antifreeze
Posts: 17,367

09-15-2020, 01:17 PM	#15
scho63 Politically Incorrect scho63's Avatar Join Date: Feb 2009 Location: Scottsdale, AZ	When I get a cold it last 24-48 hours max and it's gone. Usually just a running nose, slight chills an feeling a little weak for the day. I RARELY get a cold or flu. Sinus infections, that's a whole other story.
Posts: 50,482