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03-09-2020, 02:49 PM | #1261 | |
THE RED MENACE
Join Date: Aug 2000
Location: Texas
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03-09-2020, 02:50 PM | #1262 |
In Search of a Life
Join Date: Jan 2010
Location: L.A.
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03-09-2020, 02:52 PM | #1263 |
Life is changing..
Join Date: Jul 2012
Location: NW Missouri
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03-09-2020, 02:53 PM | #1264 | |
THE RED MENACE
Join Date: Aug 2000
Location: Texas
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03-09-2020, 02:54 PM | #1265 | |
Now you've pissed me off!
Join Date: Jan 2006
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You'd need large urban or academic centers in most cases. Quick, accurate testing (without the substantially high false positive rates of the original tests), likely confirmed by CT, which appears to be the gold standard at this point. Since there aren't other standards of care, you could treat against placebo, then see how patients did in comparison, but remember that in a disease with a small case fatality rate, marginal decreases would lead to statistically significant declines based upon how you interpret the data. Here's an example: 1000 people get coronavirus and 970 live without remdisivir. 1000 people get coronavirus and 990 live with it. What's my relative risk reduction? My event rate (death) is 3% in the control group and 1% in the experimental group. My absolute risk reduction is only 2%, but my relative risk reduction is (0.03-0.01)/(/0.03) is 66.7%, which means that I've reduced my risk of death by 2/3. Now, how many people do I need to treat to avoid 1 death? In that case, I take 1/absolute risk reduction, which is 1/(0.02), which is 50. Thus, for every 50 patients I treat with remdisivir, I prevent one excess fatality. That's pretty good from a pharmacoeconomic standpoint, but if you're treating millions of people, that's going to be a substantial financial outlay. |
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03-09-2020, 02:56 PM | #1266 | |
Now you've pissed me off!
Join Date: Jan 2006
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03-09-2020, 03:00 PM | #1267 | |
Seize life. Be an ermine.
Join Date: Jul 2001
Location: My house
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03-09-2020, 03:02 PM | #1268 | |
Supporter
Join Date: Jan 2014
Location: Missouri
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Kind of like how nobody believes you hang out with Arthur. Just like nobody should believe anything you say because you write something, then when questioned. Make shit up, like “ There is no official orthopedic surgeons for teams unless they buy the title.” Then after you say that, you then turn around and say teams have an ortho surgeon. Which is it? Do they have a team ortho or not? I have been a part of a lot of things, calling out a ****ing dipshit on the internet is a hobby I do while I watch it rain. |
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03-09-2020, 03:03 PM | #1269 |
Thread I will end you.......
Join Date: Apr 2007
Location: Kansas City, KS
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03-09-2020, 03:07 PM | #1270 |
Life is changing..
Join Date: Jul 2012
Location: NW Missouri
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So what did Italy do wrong?
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03-09-2020, 03:15 PM | #1271 |
Fight, build, win!
Join Date: Sep 2004
Location: KC
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Russia seems to be skating by not a care in the world and yet surrounded by it.
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03-09-2020, 03:19 PM | #1272 |
In Search of a Life
Join Date: Jan 2010
Location: L.A.
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Russia is the kind of place I would assume that could just call it a huge spike in viral pneumonia cases and be actually able to cover it up. Unless they're hospitals also get overwhelmed like Italy's.
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03-09-2020, 03:20 PM | #1273 |
In Search of a Life
Join Date: Jan 2010
Location: L.A.
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Well right now they seem to be the worst case outside of China (except maybe Iran but who knows). And I posted earlier itt the kind of crazy draconian things China was doing to stop the spread.
Italy seems to be figuring out the hard way what it needs to do to stop the spread. |
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03-09-2020, 03:24 PM | #1274 | |
In Search of a Life
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Location: L.A.
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https://www.smithsonianmag.com/histo...flu-180970372/ Quote:
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03-09-2020, 03:27 PM | #1275 |
MVP
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Location: Back in K.C. baby!!!!
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03-09-2020, 03:27 PM | #1276 |
MVP
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Location: Back in K.C. baby!!!!
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1 0 |
03-09-2020, 03:27 PM | #1277 |
MVP
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Location: Back in K.C. baby!!!!
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