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03-31-2020, 06:41 PM | #14401 |
Admitted Planet Junky
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03-31-2020, 06:41 PM | #14402 |
In Search of a Life
Join Date: Jul 2009
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Hamas what do you know about favipiravir?
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03-31-2020, 06:42 PM | #14403 |
In Search of a Life
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03-31-2020, 06:43 PM | #14404 |
Admitted Planet Junky
Join Date: Oct 2000
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Yes and as more and more people panic and leave the areas they live in, yes I am looking at you NYC, because the powers to be will not do what is necessary to contain this virus people will start dying from "lead".
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03-31-2020, 06:44 PM | #14405 |
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Posts: 19,375
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03-31-2020, 06:45 PM | #14406 |
Kind of a mod
Join Date: Aug 2005
Location: Donkey Land
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Posts: 52,337
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03-31-2020, 06:46 PM | #14407 |
In Search of a Life
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Posts: 24,379
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03-31-2020, 06:48 PM | #14408 |
Admitted Planet Junky
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03-31-2020, 06:50 PM | #14409 |
In Search of a Life
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Posts: 24,379
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03-31-2020, 06:51 PM | #14410 |
Life is changing..
Join Date: Jul 2012
Location: NW Missouri
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03-31-2020, 06:53 PM | #14411 |
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03-31-2020, 06:59 PM | #14412 |
Now you've pissed me off!
Join Date: Jan 2006
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Not much more than you do, probably. Upon briefly reading an article, it seems that it may not have great activity in human respiratory cells, which you'd obviously want when fighting a virus attacking alveoli. That's something that a lot of providers don't consider--drugs often have vastly different penetration depending upon what organ you are speaking of.
There is a powerful antibiotic that can be used for MRSA called Daptomycin, but you can't use it in lung infections because it is inactivated by pulmonary surfactant. Cefpodoxime is a good antibiotic, but it doesn't achieve good concentration in the urine, so it's not good against UTIs, etc. There is a Chinese study where it performed better than Kaletra with interferon alpha, but is that due to an interaction between Kaletra and interferon or is favipravir truly better? It was an open-label study, both Kaletra and interferon can be hepatotoxic (although favipravir is also hepatotoxic). It's just too hard to tell. Watching people's reactions to this reminds me of reading about early therapies thought to work against HIV. Patients (including Rock Hudson) traveled from all over the world to go to Paris to receive a drug called HPA-23, doctors actually conducted trials with a drug that was not legal to import in the US called trichosanthin (which was an extract from a Chinese root). In the end, one compound developed in the 60s was effective (AZT was a failed cancer drug developed at NIH), but it was years before truly effective therapies emerged. |
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03-31-2020, 07:02 PM | #14413 |
"Think BOOM!"
Join Date: Nov 2003
Location: 33.675° N 106.475° W
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Yep. Just stunning figures. I wish NYC had taken it more seriously. Maybe next time.
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03-31-2020, 07:06 PM | #14414 | |
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Quote:
Read one study that it had really good success with mild and moderate cases which would make some sense in regards to the respiratory issue |
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Posts: 82,344
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03-31-2020, 07:25 PM | #14415 |
King Shit of **** Mountain
Join Date: Aug 2000
Location: Texarkana, Texas
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You quarantine sick people to keep them away from the healthy. This is house arrest. Call shit what it is.
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Posts: 49,794
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