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03-30-2020, 08:20 AM | #13696 |
Best Body On ChiefsPlanet
Join Date: Jan 2014
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All you have to do is Google CoronaVirus vs The Flu and you'll get all the answers you need. Here's a good article on it.
https://www.nola.com/news/coronaviru...1dd4b.amp.html |
Posts: 5,953
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03-30-2020, 08:23 AM | #13697 |
SuperBowl or bust
Join Date: Dec 2008
Location: BF Iowa
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This is very interesting.
Hamas and Dane are 2 of the most respected posters on the site and both don’t seem to give any validity to reports of certain drugs being highly effective in battling the covid19. |
Posts: 47,198
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03-30-2020, 08:27 AM | #13698 |
Banned
Join Date: Aug 2007
Location: My house
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So now were settling science with tweets and message board opinions?
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Posts: 75,676
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03-30-2020, 08:27 AM | #13699 |
Starter
Join Date: Dec 2011
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Whether you are a Sunshine Pumper, Debbie Downer, or somewhere in between on these treatments, I think most of us can agree that the verdict on many of these treatments will be decided long before the clinical papers are printed.
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Posts: 700
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03-30-2020, 08:29 AM | #13700 | |
THIS .... IS... ARROWHEAD!!!!
Join Date: Mar 2016
Location: Houston, Tx
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Quote:
Ignore both in this instance and go around. |
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Posts: 27,646
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03-30-2020, 08:29 AM | #13701 |
In Search of a Life
Join Date: Jul 2009
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They’re starting mass serological testing in Germany to see who has had it and is immune now so that they can get out of the lock down
That’s smart |
Posts: 81,608
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03-30-2020, 08:30 AM | #13702 |
THIS .... IS... ARROWHEAD!!!!
Join Date: Mar 2016
Location: Houston, Tx
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Posts: 27,646
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03-30-2020, 08:31 AM | #13703 |
Plays to win the game!
Join Date: Mar 2005
Location: Lees Summit
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It's promising if the drugs are doing good things, but scientific testing takes longer than that to get a better overall picture. If these people all relapse, keel over, or develop cancer from these treatments then we don't have much to celebrate now do we? Extreme possibilities I know but anything is possible.
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Posts: 7,619
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03-30-2020, 08:33 AM | #13704 | |
THIS .... IS... ARROWHEAD!!!!
Join Date: Mar 2016
Location: Houston, Tx
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Quote:
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Posts: 27,646
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03-30-2020, 08:33 AM | #13705 | |
In Search of a Life
Join Date: Jul 2009
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Quote:
Yeah, we need to do our own testing to make sure it’s safe and it works |
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Posts: 81,608
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03-30-2020, 08:34 AM | #13706 | |
Now you've pissed me off!
Join Date: Jan 2006
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Quote:
It may well work. The mechanism of action (raising intracellular pH to reduce endocytosis of the virus) makes sense in a vacuum. However, and I've said this numerous times before--for every small molecule drug that is approved there are thousands--literally thousands--that fail. In vitro success does not mean in vivo success. The human body is a much different machine than even other mammals, and certainly test tubes. I'll use an extreme example: they've known about something that costs pennies that can inactivate every known virus for decades. Sodium hypochlorite in water. Well, why can't you use it: because pumping bleach into your veins will kill you. Every drug is a poison. The trick is finding a poison that kills the pathogen before it begins harming (or kills) the host. You also need to make sure that it has appropriate absorption and distribution to get where you need to it go and that it is metabolized and eliminated in a manner that avoids toxicity. People need to understand that sometimes the best answer to a question is, "I don't know." It's difficult to hear with so much information to be accessed, but the true answer right now is that we don't know. You can say that it will be effective or that it won't, but at this point, you're really just betting on sports futures, and that's not how medical decisions should be made. |
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Posts: 74,860
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03-30-2020, 08:34 AM | #13707 |
Veteran
Join Date: Jan 2020
Location: Missouri
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There is no money to be made advancing these drug treatments rapidly to registration.
If you are a University you desire complex multi level long term trials involving scads of observations... On the other hand, the drugs have been proven safe for people to take so we don't really need data on if its toxic to people, and the side effects are well known. What we don't know to a gnats ass of total accuracy is what does it do when taken by someone with this virus. And in truth that will be important to some researchers and will no doubt be studied for years. In the meantime, it would seem logical and practical to move forward and use what information can be developed with a goal of full use if the product is working. To require the usual battery of protocols and testing required for a new discovery compound is absurd. There will be so little profit in this stuff since its all generic, no one will pay for those trials anyway, and we damn sure don't need the feds shoveling more money into Universities to study things to death at high costs. |
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03-30-2020, 08:35 AM | #13708 |
"Think BOOM!"
Join Date: Nov 2003
Location: 33.675° N 106.475° W
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Posts: 182,692
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03-30-2020, 08:35 AM | #13709 |
Banned
Join Date: Aug 2007
Location: My house
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Let the scientist and medical professionals do their thing. This kind of stuff is above about 99% of the folks on this board.
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Posts: 75,676
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03-30-2020, 08:38 AM | #13710 |
THIS .... IS... ARROWHEAD!!!!
Join Date: Mar 2016
Location: Houston, Tx
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