***NON-POLITICAL COVID-19 Discussion Thread***

[JakeF]

A couple of reminders...

Originally Posted by Bwana

Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.

Originally Posted by Dartgod

People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.

California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM

The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.

“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”

The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.

The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”

Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.

The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.

The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.

A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.

Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.

“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”

It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.

“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”

On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.

“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”

According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.

More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.

But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.

“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”

CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.

Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.

“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”

[lawrenceRaider]

Originally Posted by O.city

If it produces a neutralizing antibody initially, I don't see how you wouldn't get some long term plasmoblasts and T cell initiation.

If true, then why do we "need" boosters?

[Marcellus]

Originally Posted by dirk digler

It is going to be interesting to see if there will be a mass departure of nursing home staff here shortly after it was announced yesterday that they will be required to get the vaccine or the nursing home will lose federal funding. The Feds need to apply this to all healthcare facilities that get federal funding to be honest.

You don't think just maybe FDA approval should occur before we start attaching strings to the vaccine?

[TLO]

Originally Posted by Marcellus

You don't think just maybe FDA approval should occur before we start attaching strings to the vaccine?

I'd say that's coming in the next couple of weeks

[TLO]

Real-world data out of Denmark shows overall vaccine effectiveness (both doses) against SARS-CoV-2:

Preventing Hospitalization:
Alpha- Pfizer 86%, Moderna 97%
Delta- Pfizer 94%, Moderna 97%

Preventing Infection:
Alpha- Pfizer 81%, Moderna 96%
Delta- Pfizer 79%, Moderna 88%

— Chise �������� (@sailorrooscout) August 19, 2021

[lawrenceRaider]

Originally Posted by TLO

Real-world data out of Denmark shows overall vaccine effectiveness (both doses) against SARS-CoV-2:

Preventing Hospitalization:
Alpha- Pfizer 86%, Moderna 97%
Delta- Pfizer 94%, Moderna 97%

Preventing Infection:
Alpha- Pfizer 81%, Moderna 96%
Delta- Pfizer 79%, Moderna 88%

— Chise �������� (@sailorrooscout) August 19, 2021

I was hoping for Moderna, but those shots dried up here in Wichita before my spot in line came up, so ended up wiht the Pfizer shot. My wife, who is a teacher for USD259 received Moderna, as did anyone in the school district who wanted a shot.

[Marcellus]

Originally Posted by lawrenceRaider

I was hoping for Moderna, but those shots dried up here in Wichita before my spot in line came up, so ended up wiht the Pfizer shot. My wife, who is a teacher for USD259 received Moderna, as did anyone in the school district who wanted a shot.

60% of our vaxed employees got Moderna, about 30% Pfizer, and 10% J&J.

The breakthrough numbers don't seem to favor any of the specific vaccines and seem to evenly fall in those % evenly. Sort of a small sample size of break through cases at this point though but mainly Moderna because that's what the majority have.

[TLO]

Originally Posted by lawrenceRaider

I was hoping for Moderna, but those shots dried up here in Wichita before my spot in line came up, so ended up wiht the Pfizer shot. My wife, who is a teacher for USD259 received Moderna, as did anyone in the school district who wanted a shot.

Those numbers for Pfizer are very, very good. I wouldn't stress on it.

Important to note that the numbers listed above also include asymptomatic infections.

[O.city]

Originally Posted by lawrenceRaider

If true, then why do we "need" boosters?

Based on my knowledge of immunology (which is extremely a complex subject and I'm no immunologist) this new Delta variant kind of overwhelms your innate system before Memory B cells can fire up and make enough neutralizing antibodies. So if you don't have a bunch of neutralizing antibodies floating around, you'll get infected. You're adaptive and innate system kick in to knock it down, which would be why most breakthroughs are pretty mild.

It would make sense why viral load for those immunized drops so much and so much quicker than non immune.

Technically, with the amount of time between the two doses, we got two primer doses. We probably should have gone a bit longer to get a booster, but I'm not sure it would matter.

[O.city]

Math is beautiful but often hard and sometimes counterintuitive. No wonder antivaxxers don’t get it.

But the bottom line is this: these Covid vaccines are amazing life-saving miracle drugs, without which the world would have been proper ****ed by now. pic.twitter.com/CHEGPQos4Q

— Yuri Deigin (@ydeigin) August 19, 2021

Can one of you statistically inclined fellas explain Simpsons paradox to me

[lawrenceRaider]

Originally Posted by TLO

Those numbers for Pfizer are very, very good. I wouldn't stress on it.

Important to note that the numbers listed above also include asymptomatic infections.

Yeah, I know, but if wishes were fishes and all that.

Originally Posted by O.city

Based on my knowledge of immunology (which is extremely a complex subject and I'm no immunologist) this new Delta variant kind of overwhelms your innate system before Memory B cells can fire up and make enough neutralizing antibodies. So if you don't have a bunch of neutralizing antibodies floating around, you'll get infected. You're adaptive and innate system kick in to knock it down, which would be why most breakthroughs are pretty mild.

It would make sense why viral load for those immunized drops so much and so much quicker than non immune.

Technically, with the amount of time between the two doses, we got two primer doses. We probably should have gone a bit longer to get a booster, but I'm not sure it would matter.

Thank you for the detailed answer. I appreciate it.

[Monticore]

Originally Posted by lawrenceRaider

Just saw a TV advertisement for a croup vaccine. Hadn't heard of it before.

One I didn’t know about too was RSV vaccine but expensive as hell my wife 1500$ a month x first 10 months

[lawrenceRaider]

Originally Posted by Monticore

One I didn’t know about too was RSV vaccine but expensive as hell my wife 1500$ a month x first 10 months

My kids are both past the RSV and croup danger zones I think. Daughter is almost 12 and my son is 15.

[LTL]

Originally Posted by dirk digler

It is going to be interesting to see if there will be a mass departure of nursing home staff here shortly after it was announced yesterday that they will be required to get the vaccine or the nursing home will lose federal funding. The Feds need to apply this to all healthcare facilities that get federal funding to be honest.

I think you might see a big game of chicken. I've seen it play it out somewhat in school systems. Some school systems made it a requiement to be employed. I know of a couple people that were adamant about not taking it. They were prepared to lose their jobs and even did for a short time. During the summer the school realized they didn't have enough staff to open and dropped the requirement.

Most hospital staff don't have the means to do that but i work with some that do and won't vax. Its not going to have to be a mass exodus to create problems as quite a few have already left the hospital setting for various reasons. The lower paying staff like techs and aides that don't want to i could see going that route as they can go elsewhere and make close to what they are now which would effect nursing staff and pt care.

So as you said it will be interesting.

[carlos3652]

Originally Posted by Monticore

One I didn’t know about too was RSV vaccine but expensive as hell my wife 1500$ a month x first 10 months

Damn. I had not heard of the croup vaccine. My concern is my kid (who is 2) has non stop coughing episodes over 5 min that I sooth with cold / steam air 4 times a day... Hes already done the steroid 2x over almost a 4 week period (the one you get when they sound like a seal).

Might have to go to the pediatrician again. blah.

All my coworkers are dealing with sick kids... Mouth and Foot disease, RSV and Croup have been rampant.

[carlos3652]

Originally Posted by lawrenceRaider

My kids are both past the RSV and croup danger zones I think. Daughter is almost 12 and my son is 15.

I think you are good.. my Dr's kids are 5 and 7 and they are only supposed to have a 15% chance of getting it at that age, and they had it (about 3 weeks ago)