***NON-POLITICAL COVID-19 Discussion Thread***

[JakeF]

A couple of reminders...

Originally Posted by Bwana

Once again, don't come in this thread with some kind of political agenda, or you will be shown the door. If you want to go that route, there is a thread about this in DC.

Originally Posted by Dartgod

People, there is a lot of good information in this thread, let's try to keep the petty bickering to a minimum.

We all have varying opinions about the impact of this, the numbers, etc. We will all never agree with each other. But we can all keep it civil.

Thanks!

Click here for the original OP:

Spoiler!

Apparently the CoronaVirus can survive on a inanimate objects, such as door knobs, for 9 days.

California coronavirus case could be first spread within U.S. community, CDC says
By SOUMYA KARLAMANGLA, JACLYN COSGROVE
FEB. 26, 2020 8:04 PM

The Centers for Disease Control and Prevention is investigating what could be the first case of novel coronavirus in the United States involving a patient in California who neither recently traveled out of the country nor was in contact with someone who did.

“At this time, the patient’s exposure is unknown. It’s possible this could be an instance of community spread of COVID-19, which would be the first time this has happened in the United States,” the CDC said in a statement. “Community spread means spread of an illness for which the source of infection is unknown. It’s also possible, however, that the patient may have been exposed to a returned traveler who was infected.”

The individual is a resident of Solano County and is receiving medical care in Sacramento County, according to the state Department of Public Health.

The CDC said the “case was detected through the U.S. public health system — picked up by astute clinicians.”

Officials at UC Davis Medical Center expanded on what the federal agency might have meant by that in an email sent Wednesday, as reported by the Davis Enterprise newspaper.

The patient arrived at UC Davis Medical Center from another hospital Feb. 19 and “had already been intubated, was on a ventilator, and given droplet protection orders because of an undiagnosed and suspected viral condition,” according to an email sent by UC Davis officials that was obtained by the Davis Enterprise.

The staff at UC Davis requested COVID-19 testing by the CDC, but because the patient didn’t fit the CDC’s existing criteria for the virus, a test wasn’t immediately administered, according to the email. The CDC then ordered the test Sunday, and results were announced Wednesday. Hospital administrators reportedly said in the email that despite these issues, there has been minimal exposure at the hospital because of safety protocols they have in place.

A UC Davis Health spokesperson declined Wednesday evening to share the email with The Times.

Since Feb. 2, more than 8,400 returning travelers from China have entered California, according to the state health department. They have been advised to self-quarantine for 14 days and limit interactions with others as much as possible, officials said.

“This is a new virus, and while we are still learning about it, there is a lot we already know,” Dr. Sonia Angell, director of the California Department of Public Health, said in a statement. “We have been anticipating the potential for such a case in the U.S., and given our close familial, social and business relationships with China, it is not unexpected that the first case in the U.S. would be in California.”

It is not clear how the person became infected, but public health workers could not identify any contacts with people who had traveled to China or other areas where the virus is widespread. That raises concern that the virus is spreading in the United States, creating a challenge for public health officials, experts say.

“It’s the first signal that we could be having silent transmission in the community,” said Lawrence Gostin, director of the World Health Organization Collaborating Center on National and Global Health Law. “It probably means there are many more cases out there, and it probably means this individual has infected others, and now it’s a race to try to find out who that person has infected.”

On Tuesday, the CDC offered its most serious warning to date that the United States should expect and prepare for the coronavirus to become a more widespread health issue.

“Ultimately, we expect we will see coronavirus spread in this country,” said Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Diseases. “It’s not so much a question of if, but a question of when.”

According to the CDC’s latest count Wednesday morning, 59 U.S. residents have tested positive for the new strain of coronavirus — 42 of whom are repatriated citizens from a Diamond Princess cruise. That number has grown by two since Messonnier’s last count Tuesday, although the CDC was not immediately available to offer details on the additional cases.

More than 82,000 cases of coronavirus have been reported globally, and more than 2,700 people have died, with the majority in mainland China, the epicenter of the outbreak.

But public health leaders have repeatedly reminded residents that the health risk from the novel coronavirus to the general public remains low.

“While COVID-19 has a high transmission rate, it has a low mortality rate,” the state Department of Public Health said in a statement Wednesday. “From the international data we have, of those who have tested positive for COVID-19, approximately 80% do not exhibit symptoms that would require hospitalization. There have been no confirmed deaths related to COVID-19 in the United States to date.”

CDC officials have also warned that although the virus is likely to spread in U.S. communities, the flu still poses a greater risk.

Gostin said the news of potential silent transmission does not eliminate the possibility of containing the virus in the U.S. and preventing an outbreak.

“There are few enough cases that we should at least try,” he said. “Most of us are not optimistic that that will be successful, but we’re still in the position to try.”

[TLO]

https://mobile.twitter.com/KlausKblo...44033272938496

[ptlyon]

LIGHT EM UP FELLAS!

[Mecca]

Originally Posted by TLO

https://mobile.twitter.com/KlausKblo...44033272938496

Welp I guess smokem if you gotem, for the first time in life a smoker can say it helped them.

[loochy]

Originally Posted by DaneMcCloud

And there was nothing documented by any legitimate source that said it was working to reduce viral duplication.

It was just an agenda.

Put it together (these studies are not at all new, BTW):


https://www.ncbi..nih.gov/pmc/articles/PMC4182877/


https://www.ncbi..nih.gov/pubmed/21079686




These are why I was hopeful, not because of anything Trump said. And I can't understand the people that are rooting against it because of anything Trump said. The science is (and has been) there that it should make a difference in these types of viruses.




Edit: I don't know why CP is automatically putting those little middle finger things in the middle of the links. I did not do that.

[Monticore]

Originally Posted by ptlyon

LIGHT EM UP FELLAS!

I wish I could find the "bad Idea Jeans" snl skit to embed right about now.

[OnTheWarpath15]

Originally Posted by ptlyon

LIGHT EM UP FELLAS!

It ****ing hurts to walk up a flight of steps, can't imagine sucking on a cancer stick.

[Ninerfan11]

Originally Posted by PAChiefsGuy

I don't. I want an effective vaccine to be released as quickly as possible. But at the same time I am going to realistic about it.

You're probably going to have to wait years for a vaccine. Therapies are the way out for our country, sorry to say.

['Hamas' Jenkins]

Originally Posted by Ninerfan11

I was under the impression that Hydroxy was best if administered early, why wait until they are hospitalized? The whole point of the treatment is to prevent hospitalization and overwhelming the system.

The french study clearly indicated early ingestion, I think...I'm no expert though.

I would not draw any conclusions from a study that was open-label, non-randomized, did not meet power, had a significant proportion of the patients presenting as asymptomatic, lost almost 25 percent of the intervention patients to follow-up, used a test with a known high false negative rate, and had a grand total of 42 patients.

There is absolutely nothing you could glean from that study.

Originally Posted by loochy

It would make sense, as part of it's mechanism of action is to act as an ionophore to allow zinc to enter the cell and disrupt the virus' reproduction

There are numerous potential theories for the MOA of hydroxychloroquine. It could be that it helps because it acts as an ionophore; it could be that it helps due to immunomodulatory effects; it could be that the raising of intracellular pH affects glycosylation and viral entry; it could also be that none of these are effective.

The one thing we know for sure is that there isn't yet enough data to make any kind of definitive judgment on its efficacy or lack thereof.

However, if one has followed the course of the epidemic and is also cognizant of how it has been prescribed and used, you can probably trend toward it having a minimal impact on patients, if any.

[PAChiefsGuy]

Originally Posted by loochy

So maybe a "well, that sucks" would be better than an "I told you so"?

I never once said I told you so. I was merely being humorous about ppl acting like this was a miracle drug when if you did some actual research you'd know odds of that being true were slim to none.

['Hamas' Jenkins]

Originally Posted by loochy

Put it together (these studies are not at all new, BTW):


https://www.ncbi..nih.gov/pmc/articles/PMC4182877/


https://www.ncbi..nih.gov/pubmed/21079686




These are why I was hopeful, not because of anything Trump said. And I can't understand the people that are rooting against it because of anything Trump said. The science is (and has been) there that it should make a difference in these types of viruses.




Edit: I don't know why CP is automatically putting those little middle finger things in the middle of the links. I did not do that.

1) N-L-M makes the middle finger emoji

2) In vitro is not in vivo.

If you guys learn anything from this mess, please learn that. In vitro is not in vivo. There are numerous agents that can kill this and any other virus in vitro. It does not mean it works in human studies. There is a reason why for every 5000 small molecules tried one is FDA approved.

[Monticore]

Originally Posted by loochy

Put it together (these studies are not at all new, BTW):


https://www.ncbi..nih.gov/pmc/articles/PMC4182877/


https://www.ncbi..nih.gov/pubmed/21079686




These are why I was hopeful, not because of anything Trump said. And I can't understand the people that are rooting against it because of anything Trump said. The science is (and has been) there that it should make a difference in these types of viruses.




Edit: I don't know why CP is automatically putting those little middle finger things in the middle of the links. I did not do that.

I think if people hear there is a "cure" they might not be as likely comply with social distancing , nobody is rooting against it but jumping the gun can also be damaging.

[Mecca]

Prepping for covid...

[Monticore]

Originally Posted by 'Hamas' Jenkins

1) N-L-M makes the middle finger emoji

2) In vitro is not in vivo.

If you guys learn anything from this mess, please learn that. In vitro is not in vivo. There are numerous agents that can kill this and any other virus in vitro. It does not mean it works in human studies. There is a reason why for every 5000 small molecules tried one is FDA approved.

Some even get pulled years later after being approved.

[BigRedChief]

Originally Posted by notorious

The leadership in our school is outstanding. They will call the kid and parents when work doesn't get turned in.

The local cell and internet provider stepped up to the plate and installed free internet in every kid's house that doesn't have it for FREE.

Gotta love small communities that have their shit together.

In contrast, the large cities around us have a very good plan installed, but the students and parents aren't stepping up the plate. It's just a huge contrast in culture and accountability.

Our school district(2nd largest in Florida) gave the kids free broadband and a tablet.

Originally Posted by stumppy

Same deal here. 3 kids doing their work, 1 lying through her teeth about having it all done.
So far the teachers have been really good about staying in touch.

My wife is a teacher. They are using Microsoft teams. I showed her how she can track how much her kids are not just online but what they worked on, how busy they were etc. Its just a setting you turn on. No tech skills needed. Simple interface to view the data.

[Monticore]

Originally Posted by BigRedChief

Our school district(2nd largest in Florida) gave the kids free broadband and a tablet.

My wife is a teacher. They are using Microsoft teams. I showed her how she can track how much her kids are not just online but what they worked on, how busy they were etc. Its just a setting you turn on. No tech skills needed. Simple interface to view the data.

If the kids find out , you are getting a flaming bag of turds on your doorstep. #snitchesgetstiches