The first thing Bruce Lee would do is cripple him if we're talking no-holds barred. Wouldn't even be a contest.
I took a 4 month basic self-defense/judo class and it was 80% "how to not get raped by some one with 6" and 80lbs on you" for women. I'd have to think Tyson would be wearing knee braces for the rest of his life afterwards.
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