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There may have been exotic new developments in the past year or so, but my understanding over the past 20 or so of building PCs [personal level, 5-6 for myself and 3-4 more for family, counting only from scratch not just upgrades] is that the socket drives compatibility or danger of damage.
That is, if your MOBO has a slot for the part, you're not going to damage the part by using that slot. It might be underpowered or not operating at an optimal level. But if the power and speed demands are such that a lesser rig could damage it, they update the slot or socket.
The only caveat is you might run some risk running a powerful graphics card with a shitty power supply. But 750W Plus Gold should be sufficient. The RAM and storage should affect the graphics card at all, except if they sap too much power from a shitty supply. So if you're still apprehensive, run it with just the RAM and core storage, and add additional peripherals as you gain confidence in the rig.
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